Recombinatie SREBP -1 monoklonaal antilichaam

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

SREBP-1

P36956

Human; Mouse; Rat

Recombinant Human SREBP-1 protein

BHLHD; SREBP; SREBF; BHLHD1; SREBP1; SREBF1

11A12

Unconjugated

IHC

Cardiovascular; Epigenetics and Nuclear Signaling; Cancer; Metabolism

Protein A

0.2 mg/mL

IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/wpznRa1N

IgG, κ