Recombinatie STAT6 monoklonaal antilichaam

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Stat6

P42226

Human; Mouse; Rat

Recombinant Human STAT6 protein

D12S; STAT; Signal Transducer and Activator of Transcription; D12S1644; IL-4-STAT; STAT6B; STAT6C; STAT6; IL-4 Stat; Signal Transducer and Activator of Transcription 6;12S1644; IL 4 STAT; IL4 STAT; Interleukin 4 Induced; Interleukin 4 Induced Transcription Factor IL4 STAT; interleukin4 induced; Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced; Signal Transducer And Activator Of Transcription 6 Nirs Variant 1; STAT 6; STAT interleukin4 induced; Transcription factor IL 4 STAT

6H1

Unconjugated

WB

Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Kits; Lysates; Other

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/n1jK4m1x

94 kDa

110 kDa

IgG, κ