Recombinatie TAF1 monoklonaal antilichaam

TBP (TATA-binding protein) is a ubiquitously expressed nuclear protein that functions at the core of the general transcription factor protein complex TFIID. TFIID, which contains TBP and 13 TBP-associated factors (TAFs), contributes to the formation of the transcription pre-initiation complex, an assembly of multiple protein complexes (TFIIA, TFIIB, TFIIE, TFIIF, TFIIH, and RNA polymerase II) that bind to a gene promoter during the initiation of transcription. Once the pre-initiation complex is formed, RNA polymerase II becomes competent for elongation and transcribes the body of a gene. TBP functions in the recruitment of TFIID by binding to the TATA-box sequence found approximately 25 base pairs upstream of the transcription start site of many protein-coding genes. In addition, many transcriptional activator proteins interact with TBP and various TAF proteins to facilitate recruitment of TFIID and formation of the pre-initiation complex.

TAF1

P21675

Human; Rat; Mouse

Recombinant human TAF1 fragment

TAF; CCG; KAT; DYT; MRXS; NSCL; N-TAF; TAF (II) ; DYT3/TAF; TAF1; BA2R; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; MRXS33; N-TAF1; NSCL2; OF; P250; TAF (II) 250; TAF2A; TAFII-250; TAFII250; XDP; DYT3/KAT4; N-NSCL2; TATA-box binding protein associated factor 1

A574

Unconjugated

WB

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/jmaRiVzv

213 kDa

280 kDa

IgG, κ