Recombinatie TMEM173 monoklonaal antilichaam

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

TMEM173

Q86WV6

Human; Mouse; Rat

Recombinant Human TMEM173 protein

NET; TMEM; TMEM173; ERIS; MITA; MPYS; NET23; SAVI; STING; hMITA; hSTING; Mediator of IRF3 activation; Stimulator of interferon genes protein; STING1; endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; FLJ38577; Mitochondrial mediator of IRF3 activation; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; Stimulator of interferon genes; TM173; Transmembrane protein 173

6G8

Unconjugated

WB; IHC

Immunology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Protein A

0.2 mg/mL

IHC 1:200-1000; WB 1:1000-5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/oypY9zcI

42 kDa

37 kDa

IgG, κ