Recombinatie TNF-alfa monoklonaal antilichaam

TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.

TNF

P16599

Rat

Recombinant Rat TNF-alpha Protein

MGC; Tnfsf; TNF-a; Cachectin; DIF; ICD1; ICD2; Membrane Form; MGC124630; N-terminal fragment; NTF; RATTNF; Soluble Form; TNF-alpha; Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; Tnf; Tnfa; Tnfsf2

11A12

Unconjugated

ICC/IF

Protein A

1 mg/mL

ICC/IF 1:20-1:100

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/qSULXIHS

IgG