Recombinatie WT1 monoklonaal antilichaam

Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein.

WT1

P19544

Human; Rat; Mouse

Peptide. This information is proprietary to PTMab.

AWT; FWT; NPHS; EWS-WT; WIT; WT1; AWT1; EWS-WT1; GUD; NPHS4; WAGR; WIT-2; WT33; FWT1; Wilms Tumor; Wilms tumor 1; Wilms' tumor gene; Wilms tumor protein; Wilms' tumor protein; WIT 2; WIT2; WT; WT 1; WIT 2; WT 1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1; Wilms Tumor; Wilms tumor protein; Wilms' tumor gene; Wilms' tumor protein; WIT2; WT; WT1; WT1; WT33

A742

Unconjugated

WB; IHC

Tags & Cell Markers; Epigenetics and Nuclear Signaling; Cancer; Developmental Biology

Protein A purified

1 mg/mL

WB 1:2000-1:10000; IHC 1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/C2J4vFfp

49 kDa

52 kDa

IgG, κ