REEP4 Antilichaam

REEP4 Antibody: Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature.

80346

Q9H6H4

EAW63714

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

REEP4 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1302 - Human Lung Tissue Lysate

1 mg/mL

REEP4 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

REEP4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

REEP4

Receptor accessory protein 4

Homo sapiens

Saito H, Kubota M, Roberts RW, et al. RTP family members induce functional expression of mammalian odorant receptors. Cell2004; 119:679-91.

Behrens M, Bartelt J, Reichling et al. Members of RTP and REEP gene families influence functional bitter taste receptor expression. J. Biol. Chem.2006; 281:20650-9.

Argasinska J, Rana AA, Gilchrist MJ, et al. Loss of REEP4 causes paralysis of the Xenopus embryo. Int. J. Dev. Biol.2009; 52:37-43.

REEP4 Antibody: PP432, C8orf20, PP432, Receptor expression-enhancing protein 4

ELISA, WB

119584118

Liquid