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Regorafenib N-oxide en N-desmethyl (M5) -d3-1
Gecertificeerd

Regorafenib N-oxide en N-desmethyl (M5) -d3-1

Catalog #: HY-W709612
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

Regorafenib N-oxide and N-desmethyl (M5) -d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4[1].

Product Name Alternative

N-Desmethyl regorafenib N-oxide-d3-1

UNSPSC

12352005

Target

C-Kit; Drug Metabolite; Isotope-Labeled Compounds; Raf; VEGFR

Related Pathways

MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)NC2=C(F)C([2H])=C(OC3=CC=N(C(C(N)=O)=C3)=O)C([2H])=C2[2H]

Molecular Formula

C20H10D3ClF4N4O4

Molecular Weight

487.81

References & Citations

[1]Ying-Hui Li, et al. Functional characterization of 27 CYP3A4 protein variants to metabolize regorafenib in vitro. Basic Clin Pharmacol Toxicol. 2019 Oct;125 (4) :337-344.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W709612/

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Beschrijving

Regorafenib N-oxide and N-desmethyl (M5) -d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5). Regoraf

Specificaties

ProductnaamRegorafenib N-oxide en N-desmethyl (M5) -d3-1
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-W709612

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