REL Antilichaam

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

5966

Q04864

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human REL (NP_002899.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 68kDa

IgG

WB: 1:500 - 1:2000

REL

DU145

HL-60

Raji

Mouse heart

Mouse thymus

V-rel avian reticuloendotheliosis viral oncogene homolog

Homo sapiens

REL, C-Rel

WB

Liquid