Remibrutinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1787294-07-8
LOU064
C14393-5mg
Interleukins
Immunology & Inflammation
CC1=C (C=C (C=C1NC (=O) C2=C (C=C (C=C2) C3CC3) F) F) C4=C (C (=NC=N4) N) OCCN (C) C (=O) C=C
C27H27F2N5O3
Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK) with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8 and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases.
3 years -20°C powder
Beschrijving
Remibrutinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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