Restantilichaam - middengebied: Biotine (ARP38643 P050-Biotine)

RE1-silencing transcription factor

N, NRSF, REST4, D14Mgi1, AA407358, 2610008J04Rik

19712

Q8VIG1

NP_035393

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

L3mbtl2; Htt; Nanog; Sp3; Ewsr1; Nr0b1; Syt4; Calb1; Scn2a1; Bdnf; Ascl1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

118kDa

Wet Ice

1082

REST

Rest

Rabbit

RE1-silencing transcription factor

NM_011263

ANMGMALTNDMYDLHELSKAELAAPQLIMLANVALTGEASGSCCDYLVGE