RFB4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RFB4 is a anti-CD22 monoclonal antibody. RFB4 can construct recombinant immunotoxins by fusing with copper green pseudomonas exotoxin (PE38) through disulfide bonds such as RFB4 (dsFv) -PE38. RFB4 can be used for research on cancer such as lymphoma[1][2].
505393-48-6
12352203
H302, H315, H319, H335
CD22
Immunology/Inflammation
Cancer-programmed cell death
Cancer
96.93
H302, H315, H319, H335
[1]Mansfield E, et al. Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors. Blood. 1997 Sep 1;90 (5) :2020-6.|[2]Kreitman RJ, et al. Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4 (dsFv) -PE38 at doses tolerated by cynomolgus monkeys. Int J Cancer. 1999 Mar 31;81 (1) :148-55.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991550/RFB4-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
RFB4 is a anti-CD22 monoclonal antibody. RFB4 can construct recombinant immunotoxins by fusing with copper green pseudomonas exotoxin (PE38) through disulfide b
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