RFC3 Antilichaam - N-terminalgebied: FITC (ARP46085_P050-FITC)

Replication factor C (activator 1) 3, 38kDa

RFC38

5983

P40938

NP_002906

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human RFC3

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

PCNA; TP53; UBC; RPA3; RPA2; RPA1; RPP40; FBXO6; ARFGAP1; VCP; RFC4; RFC5; RFC2; RFC1; PURB; PURA; MCM3; Cebpb; RAD21; HDGF; SMARCAD1; EBNA-LP; MESDC2; MYC; FAN1; MEPCE; USP20; CHTF8; RAD17; BRD4; CHTF18

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

RFC3 is strongly supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Zou, L., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (24), 13827-13832

Wet Ice

356

RFC3

RFC3

Rabbit

Replication factor C subunit 3

NM_002915

YHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKL

3