RFQF4

RFQF4 is a nanonet-forming peptide and antibacterial agent. RFQF4 exhibits excellent bacterial capture capability coupled with moderate antibacterial activity. RFQF4 shows bactericidal activity against E. coli, S. typhimurium, S. aureus, L. monocytogenes, and S. epidermidis (IC50: 4.89-21.85 μM) [1].

12352209

Bacterial

Anti-infection

Infection

O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC8=CC=CC=C8)C(NCC(N[C@@H](CO)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N9[C@@H](CCC9)C(N%10[C@@H](CCC%10)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

C161H232N50O34

3411.88

[1]Gao N, et al. Biomimetic Peptide Nanonets: Exploiting Bacterial Entrapment and Macrophage Rerousing for Combatting Infections. ACS Nano. 2024 Sep 17;18 (37) :25446-25464.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11132/

Peptides

No Development Reported