RFXANK Mouse Monoclonal Antibody [Kloon ID: LBI3C10]

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) RFXANK mouse monoclonal antibody, clone LBI3C10

ANKRA1; BLS; F14150_1; RFX-B

Homo sapiens regulatory factor X associated ankyrin containing protein (RFXANK), transcript variant 2, mRNA.

8625

O14593

Unconjugated

Antigen processing and presentation, Primary immunodeficiency

Antigen processing and presentation, Primary immunodeficiency

WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

RFXANK

https://www.ncbi.nlm.nih.gov/gene/?term=8625

https://www.uniprot.org/uniprot/O14593