RFXAP Antilichaam - middengebied: Biotine (ARP33226 P050-Biotine)

Regulatory factor X-associated protein

5994

O00287

NP_000529

Human, Guinea Pig

The immunogen is a synthetic peptide directed towards the middle region of human RFXAP

RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

EPS8; NHP2L1; NCL; MLLT1; HDAC4; SMARCA4; RFXANK; RFX5

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 100%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

28kDa

Long, A.B., (2006) Mol. Immunol. 43 (5), 395-409

Wet Ice

272

RFXAP

RFXAP

Rabbit

Regulatory factor X-associated protein

NM_000538

SDQALNCGGTASTGSAGNVKLEESADNILSIVKQRTGSFGDRPARPTLLE