RG7287
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RG7287 is an activating antibody inhibitor targeting human CDCP1. RG7287 prevents the loss of contact inhibition caused by the co-transformation of NIH3T3 cells with CDCP1 and Src in focus formation assays. RG7287 inhibits tumor cell proliferation and leads to a significant reduction in CDCP1 levels[1].
12352203
H302, H315, H319, H335
Others
Others
Cancer-programmed cell death
Cancer
97.666
[RG7287]
H302, H315, H319, H335
[1]Gwendlyn Kollmorgen, et al. Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy. Mol Oncol. 2013 Dec;7 (6) :1142-51.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991226/RG7287-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
RG7287 is an activating antibody inhibitor targeting human CDCP1. RG7287 prevents the loss of contact inhibition caused by the co-transformation of NIH3T3 cells
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