RGS13 Antilichaam

The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.

6003

O14921

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human RGS13 (NP_002918.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 30kDa

IgG

RGS13

Rat brain

Regulator of G-protein signaling 13

Homo sapiens

RGS13

WB, IHC

Liquid