RGS18 Antilichaam - middelste regio : HRP (ARP42805_P050-HRP)

Regulator of G-protein signaling 18

RGS13

64407

Q9NS28

NP_570138

Human, Rat, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the middle region of human RGS18

RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

APP; GNAQ; GNAI3; GNAI2; GNAI1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 79%; Horse: 86%; Human: 100%; Rat: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Wet Ice

235

RGS18

RGS18

Rabbit

Regulator of G-protein signaling 18

NM_130782

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