RHOG Antilichaam

The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1) . RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2) . RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3) .

391

P84095

NP_001656

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

RHOG antibody is affinity chromatography purified via peptide column.

Cat. No. 1305 - Human Kidney Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (87%), Guinea pig: (87%), Chicken: (87%), Pig: (71%)

RHOG antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

RHOG antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

RHOG antibody is human, mouse and rat reactive.

RHOG

Ras homolog family member G

Homo sapiens

Vincent S, Janteur P, and Fort P. Growth-regulated of rhoG, a new member of the ras homolog family. Mol. Cell Biol. 1992; 12:3138-48.

Gauthier-Rouviere C, Vignal E, Meriane M, et al. RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs. Mol. Biol. Cell 1998; 9:1379-94.

Vigorito E, Billadeu DD, Savoy D, et al. RhoG regulates gene expression and the actin skeleton in lymphocytes. Oncogene 2003; 22:330-42.

Ras homolog family member G, Rho-related GTP-binding protein, ARHG

ELISA, WB, IHC-P

46249393

Liquid