RI-OR2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RI-OR2, a retro-inverso peptide, is an amyloid-β (Aβ) oligomerization inhibitor. RI-OR2 binds to immobilized β-Amyloid (1-42) monomers and fibrils, with an apparent Kd of 9-12 μM, and also acted as an inhibitor of Aβ (1-42) fibril extension[1].
1219627-58-3
12352209
Amyloid-β
Neuronal Signaling
Neurological Disease
O=C(NCC(N[C@H](CC1=CC=CC=C1)C(N[C@H](CC2=CC=CC=C2)C(N[C@H](C(C)C)C(N[C@H](CC(C)C)C(N[C@H](CCCCN)C(NCC(N[C@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CCCNC(N)=N)NC(C)=O
C53H85N17O10
1120.35
[1]Mark Taylor, et al. Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease. Biochemistry. 2010 Apr 20;49 (15) :3261-72.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P10823/
Peptides
No Development Reported
Beschrijving
RI-OR2, a retro-inverso peptide, is an amyloid-β (Aβ) oligomerization inhibitor. RI-OR2 binds to immobilized β-Amyloid (1-42) monomers and fibrils, with an appa
Specificaties
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