RILPL1 Antilichaam

RILPL1 Antibody: While the function of the Rab interacting lysosomal protein-like 1 (RILPL1) remains unknown, the homologous protein RILP is a small GTPase that controls transport to endocytic compartments, suggesting RILPL1 may have similar functions. However, overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell, while overexpression of RILPL1 had no visible effect on the location or morphology of lysosomes.

353116

Q5EBL4

AAH89444

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

RILPL1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1473 - Rat Cerebellum Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (94%)

RILPL1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

RILPL1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.

RILPL1

Rab interacting lysosomal protein-like 1

Homo sapiens

Cantalupo G, Alifano P, Roberti V, et al. Rab-interacting lysosomal protein (RILP) : the Rab7 effector required for transport to lysosomes. EMBO J. 2001; 20:683-93

Wang T, Wong KK, and Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol. Biol. Cell 2004; 15:815-26

RILPL1 Antibody: RLP1, GOSPEL, RLP1, RILP-like protein 1, Rab-interacting lysosomal-like protein 1

ELISA, WB, IF

195947382

Liquid