Riluzolhydrochloride (standaard)

Riluzole hydrochloride (Standard) is the analytical standard of Riluzole hydrochloride. This product is intended for research and analytical applications. Riluzole hydrochloride is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

850608-87-6

12352100

GABA Receptor; Reference Standards; Sodium Channel

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Neurological Disease; Cancer

NC1=NC2=CC=C(OC(F)(F)F)C=C2S1.Cl

C8H6ClF3N2OS

270.66

[1]He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA (A) receptor function. Neuropharmacology. 2002 Feb;42 (2) :199-209.|[2]Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B0211AR/

Reference Standards