RIN2 Antilichaam

The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

54453

Q8WYP3

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 120kDa

IgG

WB: 1:500 - 1:2000

RIN2

A-549

HeLa

HepG2

Mouse heart

Mouse kidney

Ras and Rab interactor 2

Homo sapiens

MACS, RASSF4, ras and Rab interactor 2, RAB5 interacting protein 2, RAS association (RalGDS/AF-6) domain containing protein JC265, RAS association domain family 4, RAS inhibitor JC265, RAS interaction/interference protein 2

WB

Liquid