RIP3 (RIPK3) Muismonoklonale antilichamen [Kloon ID: LBI2H8]

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) RIPK3 mouse monoclonal antibody, clone LBI2H8

RIP3

Homo sapiens receptor interacting serine/threonine kinase 3 (RIPK3), mRNA.

11035

Q9Y572

Unconjugated

Cytosolic DNA-sensing pathway

Cytosolic DNA-sensing pathway

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protein Kinase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

RIPK3

https://www.ncbi.nlm.nih.gov/gene/?term=11035

https://www.uniprot.org/uniprot/Q9Y572