Rizatriptan (hemisulfaathemihydraat)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Rizatriptan (MK 462) hemisulfate hemihydrate is the agonist for 5-HT1B and 5-HT1D. Rizatriptan hemisulfate hemihydrate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system[1][2].
159776-67-7
MK 462 (hemisulfate hemihydrate)
12352211
5-HT Receptor
GPCR/G Protein; Neuronal Signaling
Neuroscience-Neuromodulation
Neurological Disease
O=S(O)(O)=O.CN(C)CCC1=CNC2=C1C=C(C=C2)CN3N=CN=C3.O.[1/2].[1/2]
C15H19N5.1/2H2O4S.1/2H2O
327.39
[1]Sciberras DG, et al. Initial human experience with MK-462 (rizatriptan) : a novel 5-HT1D agonist. Br J Clin Pharmacol. 1997 Jan;43 (1) :49-54.|[2]Cumberbatch MJ, et al. Rizatriptan has central antinociceptive effects against durally evoked responses. Eur J Pharmacol. 1997 Jun 5;328 (1) :37-40.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W018475B/
Reference compound1
Phase 4
5-HT1 Receptor
Beschrijving
Rizatriptan (MK 462) hemisulfate hemihydrate is the agonist for 5-HT1B and 5-HT1D. Rizatriptan hemisulfate hemihydrate has a peripheral vasoconstrictive effect,
Specificaties
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