RMC-4998
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2642037-07-6
Ras
Apoptosis
C57H74N8O7
RMC-4998 is a tri-complex inhibitor that selectively targets the GTP-bound state of mutant KRASG12C, with high potency for KRASG12C-CYPA tri-complex formation with an IC50 of 28 nM. It strongly inhibits ERK signaling with an IC50 of 1–10 nM and attenuates AKT/MTOR and RAL pathways, leading to potent suppression of KRASG12C-driven tumor growth and can used in cancer research.
Beschrijving
RMC-4998 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Biotin-Recombinant (sf9) Marburg virus glycoprotein (Musoke, HA-tag, >95%), purified
MVGP16-BTN
100 µL
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Hettich Centrifuge Rotanta 460R Refrigerated Large Volume
CEN0703
1 Each
X4RF Refrigerated Centrifuge
75009936
1 Each
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests