RMC-4998
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2642037-07-6
Ras
Apoptosis
C57H74N8O7
RMC-4998 is a tri-complex inhibitor that selectively targets the GTP-bound state of mutant KRASG12C, with high potency for KRASG12C-CYPA tri-complex formation with an IC50 of 28 nM. It strongly inhibits ERK signaling with an IC50 of 1–10 nM and attenuates AKT/MTOR and RAL pathways, leading to potent suppression of KRASG12C-driven tumor growth and can used in cancer research.
Beschrijving
RMC-4998 Beschikbaar in 100 mg. Bestel eenvoudig online met snelle levering.
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