RNF121 Antilichaam

RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1) . It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK) . Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1) .

552978

Q9H920

NP_060790

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

RNF121 antibody is affinity chromatography purified via peptide column.

Cat. No. 1219 - MCF7 Cell Lysate

1 mg/mL

RNF121 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

RNF121 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.

RNF121

Cat. No. 17-012 - MCF7 Cell Slide

Ring finger protein 121

Homo sapiens

Darom A, Bening-Abu-Shach U, and Broday L. RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of B-integrin. Mol. Biol. Cell 2010; 21:1788-98.

Ring finger protein 121

ELISA, WB, ICC

21361732

Liquid