Rnf170 Antilichaam

This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.

77733

Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

Mouse pancreas

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 28kDa

IgG

WB: 1:500 - 1:2000

Rnf170

Mouse testis

Ring finger protein 170

Mus musculus

6720407G21Rik, AI481227, E3 ubiquitin-protein ligase RNF17RING-type E3 ubiquitin transferase RNF170

WB

Liquid