RNF190 Polyklonale Antilichaam, AbBy FluorTM 555 Vervoeging

The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH10 (membrane-associated ring finger (C3HC4) 10), also known as RNF190 (ring finger protein 190) or MARCH-X, is an 808 amino acid protein with one RING-CH-type zinc finger domain. MARCH10 may function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation.

MARCH 10; MARCH X; MARCH-X; MARCH10; MARHA_HUMAN; Membrane associated ring finger C3HC4 10; Membrane associated ring finger C3HC4 10, E3 ubiquitin protein ligase; Membrane associated ring finger 10; Membrane associated RING finger protein 10; Membrane-associated RING finger protein 10; Membrane-associated RING-CH protein X; Probable E3 ubiquitin protein ligase MARCH10; Probable E3 ubiquitin-protein ligase MARCH10; Ring finger protein 190; RNF 190; RNF190.

162333

Human, Mouse, Rat

631-730/808

RNF190

AbBy Fluor™ 555

KLH conjugated synthetic peptide derived from human RNF190

WB, IF (IHC-P)

Purified by Protein A.

553nm/568nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

162333