RNF2 Antilichaam - middengebied: FITC (ARP34289_P050-FITC)

Ring finger protein 2

BAP1, DING, BAP-1, HIPI3, RING2, RING1B

6045

Q99496

NP_009143

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human RNF2

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2) . Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

BMI1; SCMH1; HIST2H2AC; UBE2D3; AMBRA1; WASH1; BECN1; ATG14; PIK3C3; TARDBP; SNAI1; NEDD8; UBC; EIF3I; ALYREF; RBM5; RCL1; TRIM28; CEBPZ; SUGP2; G3BP1; AKAP9; YAF2; LRPPRC; KIF20A; RAD50; ARPC4; ABCB6; SMC4; ACOT8; HNRNPDL; THOC1; THRAP3; RBM8A; KIAA0020

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

RNF2 is supported by BioGPS gene expression data to be expressed in Daudi

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

38kDa

Voncken, J.W., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2468-2473

Wet Ice

336

RNF2

RNF2

Rabbit

E3 ubiquitin-protein ligase RING2

NM_007212

NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVF