RNF8 Antilichaam - C-terminalgebied: Biotine (ARP40071 T100-Biotine)

Ring finger protein 8, E3 ubiquitin protein ligase

HRNF8

9025

O76064

NP_003949

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8

RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

TMEM79; HOMEZ; SEPT3; RBFOX2; PNMA2; USP16; WASL; HERC2; MAD1L1; VCP; TNFRSF1A; TNF; BCL10; UBE2N; UBC; NEDD8; JMJD1C; MDC1; EXOSC2; MDM2; BLM; SEPT8; SEPT7; RPSA; H2AFX; RL2; HIST2H2BE; HIST2H2AC; PCNA; RAD50; NBN; MRE11A; UBE2E3; UBE2V1; UBE2E2; UBE2E1

Biotin

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

55kDa

Lehner, B. (2004) Genome Res. 14 (7), 1315-1323

Wet Ice

485

RNF8

RNF8

Rabbit

E3 ubiquitin-protein ligase RNF8

NM_003958

MEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENE