ROBO1 Antilichaam

Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.

6091

Q9Y6N7

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1452-1651 of human ROBO1 (NP_002932.1) .

Unconjugated

Primary Antibodies

Cancer, Neuroscience

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 270kDa

IgG

ROBO1

U-251MG

HeLa

293T

U-251MG

HeLa

Roundabout, axon guidance receptor, homolog 1 (Drosophila)

Homo sapiens

ROBO1, roundabout, axon guidance receptor, homolog 1 (Drosophila), HGNC:10249, DUTT1, FLJ21882, SAX3, roundabout 1

WB, IHC, IF

Liquid