Rogaratinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1443530-05-9
BAY-1163877
C13485-1mg
FGFR
Protein Tyrosine Kinase
CC1=CC2=C (C (=C1) OC) SC (=C2) C3=C4C (=NC=NN4C (=C3COC) CN5CCNC (=O) C5) N
C23H26N6O3S
Rogaratinib (BAY-1163877) is a highly potent and selective small molecule inhibitor of pan‐FGFR kinase activity, which specifically inhibits FGFR1, 2, 3 and 4 with an IC50 values of 1.8 nM, <1 nM, 9.2 nM and 1.2 nM respectively. It demonstrates robust efficacy in cancers with altered FGFR mRNA expression.
Beschrijving
Rogaratinib Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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