RORγt-remmer 4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RORγt inhibitor 4 (Compound 9a) is an orally active and a CNS-penetrating RORγt inhibitor. RORγt inhibitor 4 improves experimental autoimmune encephalomyelitis[1].
1426803-07-7
12352005
ROR
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Inflammation/Immunology; Neurological Disease
O=C(NC1=CC(Cl)=C(C2=CC=CC=C2OC(F)(F)F)C(Cl)=C1)CC3=CC=C(S(=O)(C)=O)C=C3
C22H16Cl2F3NO4S
518.33
[1]Wang Y, et al. Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors. ACS Med Chem Lett. 2015 May 26;6 (7) :787-92.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19510/
Reference compound1
No Development Reported
RORγ
Beschrijving
RORγt inhibitor 4 (Compound 9a) is an orally active and a CNS-penetrating RORγt inhibitor. RORγt inhibitor 4 improves experimental autoimmune encephalomyelitis[
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