RPL7A Antilichaam - C-terminaal gebied: Biotine (ARP61726 P050-Biotine)

Ribosomal protein L7a

L7A, TRUP, SURF3

6130

P62424

NP_000963

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

HUWE1; UBC; TP53; SUMO2; CEP250; STAU1; MDM2; EED; RNF2; EEF1E1; AIMP1; DARS; RPL36; RPLP0; RPL26; RPL23A; RPL21; RPL15; RPL13; QARS; EIF2S1; TRAP1; PARK2; FBXO6; TARDBP; IGSF8; ICAM1; PAN2; SOCS3; UBL4A; VCAM1; ITGA4; FN1; CTBP2; MAGOH; EIF4A3; UPF1; ESR

Biotin

Polyclonal Antibody

WB

Affinity Purified

RPL7A is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

29kDa

Wet Ice

266

RPL7A

RPL7A

Rabbit

60S ribosomal protein L7a

NM_000972

KLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG