RPS6KA2 Antilichaam - middengebied HRP (ARP56170_P050-HRP)

Ribosomal protein S6 kinase, 90kDa, polypeptide 2

RSK, HU-2, RSK3, p90RSK2, p90-RSK3, pp90RSK3, MAPKAPK1C, S6K-alpha, S6K-alpha2

6196

Q15349

NP_066958

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human RPS6KA2

RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

MAPK3; MAPK1; RPS6KA1; HSP90AA1; FLNC; CSNK2B; STXBP2; NQO2; UBC; RPS6KA2; JUN; FOS; SHANK1; BAD; MAGI1; L1CAM; MAP2K1; CREB1; CREBBP

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

81kDa

Wissing, J., (2007) Mol. Cell Proteomics 6 (3), 537-547

Wet Ice

733

RPS6KA2

RPS6KA2

Rabbit

Ribosomal protein S6 kinase alpha-2

NM_021135

LSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTR