RRM1 Mouse Monoclonal Antibody [Kloon ID: UMLBI165]

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) RRM1 mouse monoclonal antibody, clone UMLBI165

R1; RIR1; RR1

Homo sapiens ribonucleotide reductase catalytic subunit M1 (RRM1), transcript variant 1, mRNA.

6240

P23921

Unconjugated

Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism

Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism

IHC 1:200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

RRM1

https://www.ncbi.nlm.nih.gov/gene/?term=6240

https://www.uniprot.org/uniprot/P23921