RS-86

RS-86 is a potent, central acting, and selective muscarinic acetylcholine receptor agonist. RS-86 exhibits typical cholinergic excitatory effects, such as inducing smooth muscle contraction, ganglion depolarization, central hypothermia, etc. RS-86 can be used for research on Alzheimer's disease[1].

3576-73-6

12352005

H302-H315-H319-H335

MAChR

GPCR/G Protein; Neuronal Signaling

Neurological Disease

O=C(C12CCN(C)CC1)N(CC)C(C2)=O

C11H18N2O2

210.27

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Palacios JM, et al. The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide) . A potent, specific muscarinic acetylcholine receptor agonist. Eur J Pharmacol. 1986 Jun 5;125 (1) :45-62.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-30647/

Reference compound2

No Development Reported