(RS) -Salsolinol (hydrobromide)

(RS) -Salsolinol hydrobromide is the hydrobromide form of (±) -Salsolinol. (RS) -Salsolinol hydrobromide is a Dopamine (HY-B0451) -derived endogenous metabolite. (RS) -Salsolinol hydrobromide activates μ-opioid receptors (MORs), reduces GABAergic transmission, increases the excitability of dopamine (DA) neurons, and thus accelerates the sustained firing of neurons in the posterior ventral tegmental area (pVTA)[2].

59709-57-8

12352005

H315-H319-H335

Endogenous Metabolite; Opioid Receptor

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Neuroscience-Neuromodulation

Neurological Disease

CC1C2=CC(O)=C(O)C=C2CCN1.Br

C10H14BrNO2

260.13

P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

[1]Xie G, et al., Salsolinol modulation of dopamine neurons. Front Behav Neurosci. 2013 May 24;7:52.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W013353/

Reference compound1

No Development Reported

Human Endogenous Metabolite