RSK1/2/3/4 (fosfo Ser221/227/S218/232) Antilichaam

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.

6195;6197;6196;27330

Q15418; P51812; Q15349; Q9UK32

NP_002944.2

Human, Mouse

RSK1/2/3/4 (phospho Ser221/227/S218/232) antibody was raised against a peptide sequence around phosphorylation site of Serine 221/227/218/232 (A-Y-S (p) -F-C) derived from Human RSK1/2/3/4.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20&#730, C for up to one year.

85 kDa

IgG

The antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at serine 221/227/218/232.

Western Blot: 1:500~1:1000

RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA6

Ribosomal protein S6 kinase, 90kDa, polypeptide 1, ribosomal protein S6 kinase, 90kDa, polypeptide 2, ribosomal protein S6 kinase, 90kDa, polypeptide 3, ribosomal protein S6 kinase, 90kDa, polypeptide 6

Homo sapiens

Moller D.E., Am. J. Physiol. 266:C351-C359 (1994) .

Gregory S.G., Nature 441:315-321 (2006) .

The MGC Project Team, Genome Res. 14:2121-2127 (2004) .

KS6A1, KS6AA, MAPKAP-K1a, RSK1

WB

55743134

Liquid