RTN4RL2 Antilichaam

RTN4RL2 Antibody: Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

349667

Q86UN3

NP_848665

Human

Unconjugated

Primary Antibodies

Neuroscience

RTN4RL2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1463 - Rat Brain Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rat: (100%), Mouse: (100%)

RTN4RL2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

RTN4RL2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Predicted: 46 kDa

IgG

Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.

RTN4RL2

Reticulon 4 receptor-like 2

Homo sapiens

Pignot V, Hein AE, Barske C, et al. Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor. J. Neurochem. 2003; 85:717-28.

Venkatesh K, Chivatakam O, Lee H, et al. The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein. J. Neurosci. 2005; 25:808-22.

RTN4RL2 Antibody: NgR2, NGRH1, NGRL3, Reticulon-4 receptor-like 2, Nogo receptor-like 3, NgR2

ELISA, WB

30425563

Liquid