RXRA Antibody - N-terminal regio : HRP (ARP43586_P050-HRP)

Retinoid X receptor, alpha

NR2B1

6256

P19793

NP_002948

Human, Mouse, Rat, Cow, Dog, Guinea Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human RXRA

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

PPARG; VDR; NCOA1; NSD1; UBC; NR1I3; NCOA4; THRB; THRA; ALOX15B; RARA; PPARA; CHD9; PRKD2; NR0B2; STAT1; NR3C2; SMAD2; GK; JAZF1; ACVR1B; NR1I2; NCOA2; PSMC5; RAD54L2; ARID5A; PML; SUMO1; ESR2; ESR1; BHLHE40; BHLHE41; NR4A1; EP300; NCOR1; NCOA6; NCOA3; TR

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

RXRA is strongly supported by BioGPS gene expression data to be expressed in HepG2, MCF7

0.5 mg/ml

Cow: 75%; Dog: 88%; Guinea Pig: 88%; Human: 100%; Mouse: 88%; Rat: 88%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

51kDa

Clark, H.F., (2008) Mol. Cell. Biol. 28 (11), 3817-3829

Wet Ice

462

RXRA

RXRA

Rabbit

Retinoic acid receptor RXR-alpha

NM_002957

DTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPI