RXRG Antilichaam - C-terminaal gebied: Biotine (ARP38881_T100-Biotine)

Retinoid X receptor, gamma

RXRC, NR2B3

6258

P48443

NP_008848

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human RXRG

RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA) . This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA) . This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

NR1H3; NR1H2; RARB; RARA; MPPED2; UBC; CUL1; DCK; NR1H4; NCOR2; NR1I2; VDR; THRB; RARG; PPARD; MAP4; CAMK2B; CEBPZ; HOXD4; AJUBA; RPAP2; LRSAM1; PNO1; CHGB; THRA; NCOA6; PPARG; SRF; CREBBP; PPARA; NR4A1; Nr0b2; ITGB3BP

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

51kDa

Bungard, C.I. Arch. Biochem. Biophys. 443 (1-2), 53-59 (2005)

Wet Ice

463

RXRG

RXRG

Rabbit

Retinoic acid receptor RXR-gamma

NM_006917

LEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT