(S, R, S) -AHPC (MDK7526)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1448297-52-6
VH032-NH2, VHL ligand 1
C15903-25mg
E3 Ligase
Ubiquitin
CC1=C (SC=N1) C2=CC=C (C=C2) CNC (=O) C3CC (CN3C (=O) C (C (C) (C) C) N) O
C22H30N4O3S
(S, R, S) -AHPC (MDK7526, VH032-NH2, VHL ligand 1) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S, R, S) -AHPC is potential useful for the targeted degradation of the androgen receptor. (S, R, S) -AHPC can be connected to the ligand for protein such as BCR-ABL1 by a linker to form PROTACs such as GMB-475. GMB-475 induces the degradation of BCR-ABL1 with IC50 of 1.11 μM in Ba/F3 cells.
3 years -20°C powder
Beschrijving
(S, R, S) -AHPC (MDK7526) Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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