(S, R, S) -AHPC-Me-CO-C4-COOH
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(S, R, S) -AHPC-Me-CO-C4-COOH is a conjugate of the E3 ligase VHL ligand and a linker, which can be used to synthesize PROTAC ERα Degrader-12. PROTAC ERα Degrader-12 is a potent and highly selective ERα PROTAC degrader[1].
2349429-73-6
12352005
H302-H315-H319
E3 Ligase Ligand-Linker Conjugates
PROTAC
Cancer
C([C@@H](NC(CCCCC(O)=O)=O)[C@@](C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
C29H40N4O6S
572.72
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
[1]Wang Y, et al. Targeted Degradation of the Estrogen Receptor α through Unconventional Coactivator Binding Site (CBS) . J Med Chem. 2025 Jul 10;68 (13) :13640-13660.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W998310/
Reference compound1
No Development Reported
Von Hippel-Lindau (VHL)
Beschrijving
(S, R, S) -AHPC-Me-CO-C4-COOH is a conjugate of the E3 ligase VHL ligand and a linker, which can be used to synthesize PROTAC ERα Degrader-12. PROTAC ERα Degrad
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
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1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS pipette, variable vol µme 1000~10000 µL
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