Safusidenib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1898206-17-1
AB-291; DS-1001
C15153-5mg
O=C (N1C2=CC=CC (/C=C/C (O) =O) =C2C (C) =C1) C3=C (C (C) (F) C) ON=C3C4=C (C=C (C=C4Cl) Cl) Cl
C25H18Cl3FN2O4
Safusidenib (AB-291; DS-1001) is an orally bioavailable, selective inhibitor of mutant IDH1. It demonstrates potent inhibition against mutant IDH1 while showing minimal activity against the wild-type enzyme. The compound exhibits antitumor effects in chondrosarcoma models. In vitro assays without preincubation, safusidenib inhibits IDH1R132H and IDH1R132C with IC50 values of 15 nM and 130 nM, respectively.
Beschrijving
Safusidenib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
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1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
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1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS pipette, variable vol µme 1000~10000 µL
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