SALL3 Antilichaam: HRP (ARP39971_P050-HRP)

Sal-like 3 (Drosophila)

ZNF796

27164

Q9BXA9

NP_741996

Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish

The immunogen is a synthetic peptide directed towards the following sequence RRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSV

This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.

DNMT3A; CHD7; UBC; SOX2

HRP: Horseradish Peroxidase

Polyclonal Antibody

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 79%; Human: 100%; Mouse: 100%; Pig: 85%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

135 kDa

Wet Ice

1300

SALL3

SALL3

Rabbit

Sal-like protein 3

NM_171999

RRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSV