Sanguinarine (chloride) -13C, d3

Sanguinarine chloride-13C, d3 (Sanguinarin chloride-13C, d3) is the deuterium labeled Sanguinarine chloride. Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

Sanguinarin (chloride) -13C, d3; Sanguinarium (chloride) -13C, d3; Pseudochelerythrine (chloride) -13C, d3

12352005

Apoptosis; Autophagy; Bacterial; Isotope-Labeled Compounds; Parasite

Anti-infection; Apoptosis; Autophagy; Others

Cancer

[2H][13C]([2H])([N+]1=CC2=C(C3=C1C4=CC5=C(C=C4C=C3)OCO5)C=CC6=C2OCO6)[2H].[Cl-]

C19 13CH11D3ClNO4

371.79

[1]Wang Y, Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species. Oncotarget. 2016 Apr 19;7 (16) :22355-67.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W768895/

Isotope-Labeled Compounds

No Development Reported